The ECDC Communicable Disease Threats Report (CDTR) is a weekly bulletin for epidemiologists and health professionals on active public health threats. This issue covers covers the period 20 -26 September 2020 and includes updates on COVID-19 associated with SARS-CoV-2, West Nile virus, Ebola virus disease – eleventh outbreak in the Democratic Republic of the Congo, Chikungunya and dengue.